GO Term : GO:0004799 thymidylate synthase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0004799 404548  
OntologyAnnotation GO:0004799 404548 GO
GOAnnotation GO:0004799 evm.TU.supercontig_106.15  
OntologyAnnotation GO:0004799 evm.model.supercontig_106.15 GO
OntologyAnnotation GO:0004799 30131.m007071 GO
GOAnnotation GO:0004799 30131.t000222  
GOAnnotation GO:0004799 30170.t000494  
OntologyAnnotation GO:0004799 30170.m014082 GO
OntologyAnnotation GO:0004799 Cucsa.109460.1 GO
OntologyAnnotation GO:0004799 Cucsa.109460.2 GO
GOAnnotation GO:0004799 Cucsa.109460  
OntologyAnnotation GO:0004799 Cucsa.109460.9 GO
OntologyAnnotation GO:0004799 orange1.1g009747m GO
GOAnnotation GO:0004799 orange1.1g009747m.g  
OntologyAnnotation GO:0004799 orange1.1g010303m GO
OntologyAnnotation GO:0004799 orange1.1g009746m GO
OntologyAnnotation GO:0004799 orange1.1g009737m GO
OntologyAnnotation GO:0004799 orange1.1g010811m GO
GOAnnotation GO:0004799 AT2G16370  
OntologyAnnotation GO:0004799 AT2G16370.1 GO
OntologyAnnotation GO:0004799 AT2G21550.1 GO
GOAnnotation GO:0004799 AT2G21550  
GOAnnotation GO:0004799 AT4G34570  
OntologyAnnotation GO:0004799 AT4G34570.1 GO
GOAnnotation GO:0004799 Thhalv10024973m.g  
OntologyAnnotation GO:0004799 Thhalv10024973m GO
GOAnnotation GO:0004799 Thhalv10022646m.g  
OntologyAnnotation GO:0004799 Thhalv10022646m GO
GOAnnotation GO:0004799 Thhalv10000156m.g  
OntologyAnnotation GO:0004799 Thhalv10000156m GO

10 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0008168 methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0032259 methylation The process in which a methyl group is covalently attached to a molecule.
GO:0004799 thymidylate synthase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0016741 transferase activity, transferring one-carbon groups Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor).
GO:0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate.

9 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0042083 GO:0004799
part of GO:0032259 GO:0004799
is_a GO:0016741 GO:0004799
is_a GO:0003674 GO:0004799
is_a GO:0008168 GO:0004799
is_a GO:0016740 GO:0004799
part of GO:0008150 GO:0004799
part of GO:0008152 GO:0004799
is_a GO:0003824 GO:0004799

5 Synonyms

Name Type
methylenetetrahydrofolate:dUMP C-methyltransferase activity synonym
dTMP synthase activity synonym
TMP synthetase activity synonym
thymidylate synthetase activity synonym
5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity synonym