GO Term : GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine GO

Namespace:  biological_process Obsolete:  false
description  The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0017183 110295  
OntologyAnnotation GO:0017183 110295 GO
GOAnnotation GO:0017183 232025  
OntologyAnnotation GO:0017183 232025 GO
OntologyAnnotation GO:0017183 evm.model.supercontig_1059.3 GO
GOAnnotation GO:0017183 evm.TU.supercontig_1059.3  
GOAnnotation GO:0017183 evm.TU.supercontig_9.352  
OntologyAnnotation GO:0017183 evm.model.supercontig_9.352 GO
OntologyAnnotation GO:0017183 29641.m000377 GO
GOAnnotation GO:0017183 29641.t000002  
GOAnnotation GO:0017183 30170.t000637  
OntologyAnnotation GO:0017183 30170.m014225 GO
GOAnnotation GO:0017183 Cucsa.095250  
OntologyAnnotation GO:0017183 Cucsa.095250.1 GO
GOAnnotation GO:0017183 Cucsa.159800  
OntologyAnnotation GO:0017183 Cucsa.159800.1 GO
GOAnnotation GO:0017183 orange1.1g023387m.g  
OntologyAnnotation GO:0017183 orange1.1g031196m GO
OntologyAnnotation GO:0017183 orange1.1g027789m GO
OntologyAnnotation GO:0017183 orange1.1g030179m GO
OntologyAnnotation GO:0017183 orange1.1g027097m GO
OntologyAnnotation GO:0017183 orange1.1g027088m GO
OntologyAnnotation GO:0017183 orange1.1g023387m GO
OntologyAnnotation GO:0017183 orange1.1g027091m GO
OntologyAnnotation GO:0017183 orange1.1g011028m GO
GOAnnotation GO:0017183 orange1.1g011028m.g  
OntologyAnnotation GO:0017183 orange1.1g020984m GO
OntologyAnnotation GO:0017183 orange1.1g014409m GO
OntologyAnnotation GO:0017183 orange1.1g014283m GO
OntologyAnnotation GO:0017183 orange1.1g014264m GO

23 Parents

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO:0006464 cellular protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0043412 macromolecule modification The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0018193 peptidyl-amino acid modification The alteration of an amino acid residue in a peptide.
GO:0044267 cellular protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0044711 single-organism biosynthetic process A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - involving a single organism.
GO:0036211 protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GO:0018202 peptidyl-histidine modification The modification of peptidyl-histidine.
GO:0017182 peptidyl-diphthamide metabolic process The chemical reactions and pathways involving peptidyl-diphthamide, a modified histidine residue.

22 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0017182 GO:0017183
is_a GO:0044763 GO:0017183
is_a GO:0044711 GO:0017183
is_a GO:0044249 GO:0017183
is_a GO:0018202 GO:0017183
is_a GO:0044267 GO:0017183
is_a GO:0043412 GO:0017183
is_a GO:0044238 GO:0017183
is_a GO:0044699 GO:0017183
is_a GO:0044710 GO:0017183
is_a GO:0044237 GO:0017183
is_a GO:0018193 GO:0017183
is_a GO:0009987 GO:0017183
is_a GO:0009058 GO:0017183
is_a GO:0008152 GO:0017183
is_a GO:0036211 GO:0017183
is_a GO:0006464 GO:0017183
is_a GO:0008150 GO:0017183
is_a GO:0044260 GO:0017183
is_a GO:0019538 GO:0017183
is_a GO:0071704 GO:0017183
is_a GO:0043170 GO:0017183

3 Synonyms

Name Type
peptidyl-diphthamide synthesis from peptidyl-histidine synonym
peptidyl-diphthamide formation from peptidyl-histidine synonym
peptidyl-diphthamide anabolism from peptidyl-histidine synonym