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GO:0003824
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catalytic activity
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Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
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GO:0008152
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metabolic process
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The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. |
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GO:0008168
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methyltransferase activity
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Catalysis of the transfer of a methyl group to an acceptor molecule. |
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GO:0044237
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cellular metabolic process
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The chemical reactions and pathways by which individual cells transform chemical substances. |
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GO:0018024
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histone-lysine N-methyltransferase activity
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Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives. |
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GO:0008757
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S-adenosylmethionine-dependent methyltransferase activity
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Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate. |
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GO:0019538
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protein metabolic process
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The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification. |
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GO:0051276
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chromosome organization
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A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome. |
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GO:0016740
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transferase activity
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Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. |
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GO:0016568
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chromatin modification
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The alteration of DNA, protein, or sometimes RNA, in chromatin, which may result in changing the chromatin structure. |
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GO:0006464
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cellular protein modification process
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The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). |
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GO:0071704
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organic substance metabolic process
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The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. |
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GO:0006479
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protein methylation
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The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. |
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GO:0016570
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histone modification
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The covalent alteration of one or more amino acid residues within a histone protein. |
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GO:0043412
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macromolecule modification
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The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. |
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GO:0032259
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methylation
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The process in which a methyl group is covalently attached to a molecule. |
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GO:0044238
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primary metabolic process
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The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. |
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GO:0008276
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protein methyltransferase activity
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Catalysis of the transfer of a methyl group (CH3-) to a protein. |
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GO:0008170
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N-methyltransferase activity
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Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule. |
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GO:0016571
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histone methylation
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The modification of histones by addition of methyl groups. |
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GO:0034968
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histone lysine methylation
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The modification of a histone by addition of one or more methyl groups to a lysine residue. |
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GO:0051568
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histone H3-K4 methylation
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The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone. |
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GO:0044260
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cellular macromolecule metabolic process
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The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. |
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GO:0016279
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protein-lysine N-methyltransferase activity
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Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate. |
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GO:0018193
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peptidyl-amino acid modification
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The alteration of an amino acid residue in a peptide. |
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GO:0016043
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cellular component organization
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A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. |
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GO:0044267
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cellular protein metabolic process
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The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification. |
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GO:0009987
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cellular process
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Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
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GO:0006325
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chromatin organization
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Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. |
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GO:0006996
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organelle organization
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A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. |
