GO Term : GO:0007095 mitotic G2 DNA damage checkpoint GO
Namespace:  biological_process Obsolete:  false
description  A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.
Paste the following link

0 Cross References

0 Data Sets

1 Ontology

Name
GO

2 Ontology Annotations

Class GO Term Gene Name Db
OntologyAnnotation GO:0007095 Zosma03g21070 GO
GOAnnotation GO:0007095 Zosma03g21070  

45 Parents

Identifier Name Description
GO:0007049 cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
GO:0051726 regulation of cell cycle Any process that modulates the rate or extent of progression through the cell cycle.
GO:0007093 mitotic cell cycle checkpoint A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
GO:0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0000077 DNA damage checkpoint A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds.
GO:0000075 cell cycle checkpoint A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction.
GO:0006974 cellular response to DNA damage stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
GO:0000278 mitotic cell cycle Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0007095 mitotic G2 DNA damage checkpoint A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0033554 cellular response to stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:1903047 mitotic cell cycle process A process that is part of the mitotic cell cycle.
GO:0022402 cell cycle process The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.
GO:0031570 DNA integrity checkpoint A cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.
GO:0044772 mitotic cell cycle phase transition The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase.
GO:0044770 cell cycle phase transition The cell cycle process by which a cell commits to entering the next cell cycle phase.
GO:0000086 G2/M transition of mitotic cell cycle The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
GO:0044839 cell cycle G2/M phase transition The cell cycle process by which a cell in G2 phase commits to M phase.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0045786 negative regulation of cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
GO:1901991 negative regulation of mitotic cell cycle phase transition Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition.

79 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0031572 GO:0007095
part of GO:0000278 GO:0007095
is_a GO:0031572 GO:0007095
part of GO:0000278 GO:0007095
is_a GO:0044773 GO:0007095
is_a GO:0044818 GO:0007095
part of GO:0044763 GO:0007095
is_a GO:0007346 GO:0007095
is_a GO:0033554 GO:0007095
regulates GO:0009987 GO:0007095
is_a GO:0031570 GO:0007095
is_a GO:1901991 GO:0007095
is_a GO:0000075 GO:0007095
is_a GO:1901990 GO:0007095
regulates GO:0007049 GO:0007095
negatively regulates GO:1903047 GO:0007095
is_a GO:0050896 GO:0007095
part of GO:0008150 GO:0007095
is_a GO:0008150 GO:0007095
is_a GO:0044763 GO:0007095
is_a GO:0045930 GO:0007095
is_a GO:0048523 GO:0007095
negatively regulates GO:0044839 GO:0007095
is_a GO:1901988 GO:0007095
is_a GO:1901987 GO:0007095
negatively regulates GO:0022402 GO:0007095
negatively regulates GO:0007049 GO:0007095
negatively regulates GO:0009987 GO:0007095
part of GO:0044699 GO:0007095
is_a GO:1902750 GO:0007095

1 Synonyms

Name Type
mitotic cell cycle G2/M transition DNA damage checkpoint synonym