Protein Domain : IPR030700

Type:  Family Name:  Arginine-tRNA-protein transferase
Description:  Arginine-tRNA-protein transferase catalyses the post-translational conjugation of arginine to the N terminus of a protein. In eukaryotes, this functions as part of the N-end rule pathway of protein degradation by conjugating a destabilising amino acid to the N-terminal aspartate or glutamate of a protein, targeting the protein for ubiquitin-dependent proteolysis []. In Saccharomyces cerevisiae, Cys20, 23, 94 and/or 95 are thought to be important for activity []. Of these, only Cys 94 appears to be completely conserved in this family. Short Name:  Arg-tRNA_Trfase
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2 Child Features

DB identifier Type Name
IPR017137 Family Arginine-tRNA-protein transferase 1, eukaryotic
IPR017138 Family Putative arginyl-tRNA--protein transferase, prokaryotic

0 Contains

1 Cross References

Identifier
PTHR21367:SF0

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

2 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Zosma01g40820 PAC:50093979 Zostera marina 562  
Zosma07g00800 PAC:50101764 Zostera marina 309  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9858543
            7495814