| Type: | Family | Name: | 3-amino-5-hydroxybenzoic acid synthesis-related |
| Description: | The enzymes in this family are all located in the operons for the biosynthesis of 3-amino-5-hydroxybenzoic acid (AHBA), which is a precursor of several antibiotics including ansatrienin [], naphthomycin [], rifamycin [] and mitomycin []. The role that this enzyme plays in this biosynthesis has not been elucidated. It is a member of the haloacid dehalogenase superfamily of aspartate-nucleophile hydrolases. This enzyme is closely related to phosphoglycolate phosphatase (), but it is unclear what purpose a PGPase or PGPase-like activity would serve in these biosyntheses. The family is restricted to the Gram-positive actinobacteria. | Short Name: | AHBA_synth-like |
