Protein Domain : IPR000204

Type:  Family Name:  Orexin receptor family
Description:  The neuropeptide hormone orexin stimulates appetite and food consumption [], and is found in the hypothalamus, which has been shown to be the 'feeding centre' and plays a central role in the integrated control of feeding and energy homeostasis []. It also has a prominent role in promoting wakefulness [, , ]. The orexin receptor (also referred to as the hypocretin receptor) is a rhodopsin-like G protein-coupled receptor that binds orexin. There are two subtypes; orexin receptor 1 (OX1) and orexin receptor 2 (OX2) [].This entry represents the orexin receptor family. Short Name:  Orexin_rcpt

2 Child Features

DB identifier Type Name
IPR004060 Family Orexin receptor 2
IPR004059 Family Orexin receptor 1

0 Contains

1 Cross References

Identifier
PR01064

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0016499 IPR000204
GO:0007186 IPR000204
GO:0007631 IPR000204
GO:0016021 IPR000204

4 Ontology Annotations

GO Term Gene Name
GO:0016499 IPR000204
GO:0007186 IPR000204
GO:0007631 IPR000204
GO:0016021 IPR000204

1 Parent Features

DB identifier Type Name
IPR000276 Family G protein-coupled receptor, rhodopsin-like

0 Proteins

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9491897
            9656726
            10458611
            10615891
            10481909
            16507882