1 Child Features
DB identifier | Type | Name |
---|---|---|
IPR023427 | Family | Acetyl-CoA decarbonylase/synthase complex, gamma subunit, archaea |
3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0005506 | IPR016218 |
GO:0008168 | IPR016218 |
GO:0046356 | IPR016218 |
Type: | Family | Name: | Acetyl-CoA decarbonylase/synthase complex, gamma subunit |
Description: | This group represents the gamma subunit of acetyl-CoA decarbonylase/synthase (ACDS), a complex catalysing the reversible cleavage of acetyl-CoA. Depending on the direction of the reaction this complex allows either growth on acetate as sole carbon and energy source, or autotrophic growth from carbon dioxide/carbon monoxide [].The ACDS complex contains five subunits, among which beta possesses an Ni-Fe-S active-site metal cluster, the A-cluster, at which reaction with acetyl-CoA takes place, generating an acetyl-enzyme species poised for C-C bond cleavage []. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta chains with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).Titration experiments indicate that two electrons are required for activation of the enzyme in the process of forming the enzyme-acetyl intermediate []. | Short Name: | AcylCoA_decarb/synth_gsu |
DB identifier | Type | Name |
---|---|---|
IPR023427 | Family | Acetyl-CoA decarbonylase/synthase complex, gamma subunit, archaea |
GO Term | Gene Name |
---|---|
GO:0005506 | IPR016218 |
GO:0008168 | IPR016218 |
GO:0046356 | IPR016218 |