Type: | Family | Name: | tRNA-splicing endonuclease, archaeal long subfamily |
Description: | tRNA-splicing endonucleases () catalyse the endonucleolytic cleavage of pre tRNA at the 5' and 3' splice sites to release the intron and produces two half tRNA molecules bearing 5' hydroxyl and 2', 3'-cyclic phosphate termini [, ]. The genes encoding these proteins are homologous in eukaryotes and archea. The eukaryotic tRNA-splicing endonucleases are heterotetrameric while the archaeal endonucleases can be split into homodimeric and homotetrameric subgroups.This group represents the archaeal long tRNA-splicing endonucleases subfamily. | Short Name: | tRNA_splic_arch_long |