Protein Domain : IPR028705

Type:  Family Name:  Stromelysin-3
Description:  Matrix metalloproteinases (MMPs) are zinc-dependent and calcium-dependent proteases that degrade most components of the extracellular matrix (ECM) and process a number of bioactive molecules.Stromelysin-3 (also known as MMP11) may play an important role in the progression of epithelial malignancies []. It is expressed in tissues undergoing the active remodelling associated with embryonic development, wound healing and tumour invasion. Stromelysin-3 is activated by furin, a Golgi-associated proteinase []. Short Name:  Stromelysin-3

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10201:SF20

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004222 IPR028705
GO:0006508 IPR028705
GO:0007275 IPR028705

3 Ontology Annotations

GO Term Gene Name
GO:0004222 IPR028705
GO:0006508 IPR028705
GO:0007275 IPR028705

1 Parent Features

DB identifier Type Name
IPR016293 Family Peptidase M10A, stromelysin-type

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1701851
            7746327