Type: | Conserved_site | Name: | Actinin-type actin-binding domain, conserved site |
Description: | Alpha-actinin is a F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures []. The actin-binding domain of alpha-actinin seems to reside in the first 250 residues of the protein. A similar actin-binding domain has been found in the N-terminal region of many different actin-binding proteins [, ], like the beta chain of spectrin (or fodrin), dystrophin, the slime mold gelation factor (or ABP-120), filamin and fimbrin.This entry represents two conserved sites for the actin-binding domain. | Short Name: | Actinin_actin-bd_CS |