Type: | Conserved_site | Name: | Nucleoside phosphorylase, conserved site |
Description: | The following phosphorylases are in the same family:Purine nucleoside phosphorylase () (PNP) from most bacteria (gene deoD), which catalyses the cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules [].Uridine phosphorylase () (UdRPase) from bacteria (gene udp) and mammals, which catalyses the cleavage of uridine into uracil and ribose-1-phosphate, the products of the reaction are used either as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis [].5'-methylthioadenosine phosphorylase () (MTA phosphorylase) from Sulfolobus solfataricus[].It should be noted that mammalian and some bacterial PNP as well as eukaryotic MTA phosphorylase belong to a different family of phosphorylases. | Short Name: | Nucleoside_phosphorylase_CS |