Protein Domain : IPR010058

Type:  Family Name:  Uridine phosphorylase
Description:  This entry represents a family of bacterial and archaeal uridine phosphorylases unrelated to the mammalian enzymes of the same name. The Escherichia coli[], Salmonella [] and Klebsiella [] genes have been characterised. Sequences from Clostridium, Streptomyces, Treponema, Aeropyrum and Pyrobaculum are also included in this family, but it does not include related sequences from Halobacterium, which are more distantly related and represent enzymes with a slightly different substrate specificity. Also distantly related is a clade of archaeal sequences which are related to the DeoD family of inosine phosphorylases () as they are to these uridine phosphorylases. This clade includes a characterised protein from Sulfolobus solfataricuswhich has been misnamed as a methylthioadenosine phosphorylase, but which acts on inosine and guanosine - it is unclear whether uridine has been evaluated as a substrate []. Short Name:  Uridine_phosphorylase
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0 Child Features

1 Contains

DB identifier Type Name
IPR018016 Conserved_site Nucleoside phosphorylase, conserved site

1 Cross References

Identifier
TIGR01718

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004850 IPR010058
GO:0009166 IPR010058
GO:0005737 IPR010058

3 Ontology Annotations

GO Term Gene Name
GO:0004850 IPR010058
GO:0009166 IPR010058
GO:0005737 IPR010058

1 Parent Features

DB identifier Type Name
IPR018017 Family Nucleoside phosphorylase

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8534998
            7929153
            9526114
            16751