Protein Domain : IPR028416

Type:  Family Name:  Suppressor of cytokine signalling 4
Description:  SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS4 (Suppressor of cytokine signalling 4) is the substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins []. SOCS4 and SOCS5 regulate epidermal growth factor receptor signaling []. Short Name:  SOCS4
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10385:SF29

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0007175 IPR028416
GO:0032436 IPR028416

2 Ontology Annotations

GO Term Gene Name
GO:0007175 IPR028416
GO:0032436 IPR028416

1 Parent Features

DB identifier Type Name
IPR028413 Family Suppressor of cytokine signalling

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15590694
            17997974