| Type: | Family | Name: | Cytokine-inducible SH2-containing protein |
| Description: | Cytokine-inducible SH2-containing protein (CIS) is a member of the suppressor of cytokine signaling (SOCS) family proteins. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. It inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation []. | Short Name: | CIS |
