| Type: | Conserved_site | Name: | Glycoside hydrolase, family 8, conserved site |
| Description: | O-Glycosyl hydrolases () are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [, ]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.Glycoside hydrolase family 8 comprises enzymes with several known activities; endoglucanase (); lichenase (); chitosanase (). These enzymes were formerly known as cellulase family D []. The most conserved region in these enzymes is a stretch of about 20 residues that contains two conserved aspartates. The first asparatate is thought [] to act as the nucleophile in the catalytic mechanism. This region as a signature pattern in this entry. | Short Name: | Glyco_hydro_8_CS |
