Protein Domain : IPR008928

Type:  Domain Name:  Six-hairpin glycosidase-like
Description:  The biosynthesis of disaccharides, oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. A classification of glycosyltransferases using nucleotide diphospho-sugar, nucleotide monophospho-sugar and sugar phosphates () and related proteins into distinct sequence based families has been described []. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. The same three-dimensional fold is expected to occur within each of the families. Because 3-D structures are better conserved than sequences, several of the families defined on the basis of sequence similarities may have similar 3-D structures and therefore form 'clans'.The six-hairpin glycoside transferase domain contains up to seven alpha-hairpins arranged in closed circular array. Protein families that contain domains with this structure include glucoamylases, various endocellulases and exocellulases (catalytic domain), N-acyl-D-glucosamine 2-epimerases, bacterial maltose phosphorylase (central domain), and bacterial glucoamylases (C-terminal domain). Short Name:  6-hairpin_glycosidase-like
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3 Child Features

DB identifier Type Name
IPR012341 Domain Six-hairpin glycosidase
IPR031335 Domain Glycosyl hydrolase family 63, C-terminal
IPR008902 Domain Bacterial alpha-L-rhamnosidase

5 Contains

DB identifier Type Name
IPR012341 Domain Six-hairpin glycosidase
IPR019834 Conserved_site Glycoside hydrolase, family 8, conserved site
IPR018221 Active_site Glycoside hydrolase, family 9, active site
IPR005194 Domain Glycoside hydrolase family 65, C-terminal
IPR018232 Conserved_site Glycoside hydrolase, family 37, conserved site

1 Cross References

Identifier
SSF48208

15 Found Ins

DB identifier Type Name
IPR020464 Family LanC-like protein, eukaryotic
IPR012878 Family Beta-L-arabinofuranosidase, GH127
IPR001661 Family Glycoside hydrolase, family 37
IPR016518 Family Alpha-L-fucosidase
IPR014551 Family Beta-glucosidase GBA2-type
IPR006775 Domain Glucosylceramidase
IPR010401 Family Glycogen debranching enzyme
IPR008313 Family Uncharacterised conserved protein UCP028846
IPR004888 Family Glycoside hydrolase, family 63
IPR005198 Family Glycoside hydrolase, family 76
IPR006421 Family Glycogen debranching enzyme, metazoa
IPR006451 Family Glycogen debranching enzyme, archaeal type
IPR014512 Family Predicted O-glycosyl hydrolase
IPR017045 Family Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase
IPR008734 Family Phosphorylase kinase alpha/beta subunit

1 GO Annotation

GO Term Gene Name
GO:0003824 IPR008928

1 Ontology Annotations

GO Term Gene Name
GO:0003824 IPR008928

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
171005 D8RFF6 PAC:15405745 Selaginella moellendorffii 791  
92385 D8RGA8 PAC:15417747 Selaginella moellendorffii 983  
93949 D8RHA1 PAC:15402765 Selaginella moellendorffii 72  
99802 D8RRD2 PAC:15419508 Selaginella moellendorffii 646  
30650 D8RTM4 PAC:15415627 Selaginella moellendorffii 755  
267827 D8RVI5 PAC:15414339 Selaginella moellendorffii 476  
415162 D8RV79 PAC:15418045 Selaginella moellendorffii 468  
165919 D8QXV8 PAC:15417204 Selaginella moellendorffii 853  
151264 D8RZD9 PAC:15415464 Selaginella moellendorffii 467  
109529 D8S600 PAC:15404892 Selaginella moellendorffii 666  
109304 D8S5R2 PAC:15403338 Selaginella moellendorffii 557  
177119 D8S5R3 PAC:15401789 Selaginella moellendorffii 613  
443960 D8S5V5 PAC:15417616 Selaginella moellendorffii 606  
166634 D8QZD7 PAC:15417861 Selaginella moellendorffii 916  
110264 D8S733 PAC:15405947 Selaginella moellendorffii 106  
111393 D8S8U3 PAC:15409730 Selaginella moellendorffii 488  
117027 D8SHH6 PAC:15402465 Selaginella moellendorffii 487  
234337 D8SK42 PAC:15402364 Selaginella moellendorffii 500  
266914 D8R371 PAC:15412088 Selaginella moellendorffii 464  
156751 D8SMS9 PAC:15411525 Selaginella moellendorffii 594  
234652 D8SNP2 PAC:15404650 Selaginella moellendorffii 622  
144066 D8R6S0 PAC:15415509 Selaginella moellendorffii 472  
85183 D8R5W0 PAC:15417783 Selaginella moellendorffii 495  
266522 D8QPV4 PAC:15409004 Selaginella moellendorffii 620  
1701 D8T0H7 PAC:15409257 Selaginella moellendorffii 354  
90006 D8RAY7 PAC:15409415 Selaginella moellendorffii 549  
89558 D8RBK2 PAC:15410189 Selaginella moellendorffii 562  
89765 D8RBB4 PAC:15411740 Selaginella moellendorffii 797  
75214 D8QMQ2 PAC:15411249 Selaginella moellendorffii 613  
437793 D8QTR2 PAC:15420624 Selaginella moellendorffii 488  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9334165