Protein Domain : IPR001760

Type:  Family Name:  Opsin
Description:  Visual pigments [, ] are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to the chromophore cis-retinal. Vision is effected through the absorption of a photon by cis-retinal which is isomerised to trans-retinal. This isomerisation leads to a change of conformation of the protein. Opsins are integral membrane proteinswith seven transmembrane regions that belong to family 1 of G-protein coupled receptors. In vertebrates four different pigments are generally found. Rod cells, which mediate vision in dim light, contain the pigment rhodopsin. Cone cells, which function in bright light, are responsible for colour vision and contain three or more colour pigments (for example, in mammals: red, blue and green). In Drosophila, the eye is composed of 800 facets or ommatidia. Each ommatidium contains eight photoreceptor cells (R1-R8): the R1 to R6 cells are outer cells, R7 and R8 inner cells. Each of the three types of cells (R1-R6, R7 and R8) expresses a specific opsin.Proteins evolutionary related to opsins include: Squid retinochrome, also known as retinal photoisomerase, which converts various isomers of retinal into 11-cis retinal.Mammalian opsin 3 (Encephalopsin) that may play a role in encephalic photoreception.Mammalian opsin 4 (Melanopsin) that may mediate regulation of circadian rhythms and acute suppression of pineal melatonin.Mammalian retinal pigment epithelium (RPE) RGR [], a protein that may also act in retinal isomerisation. Short Name:  Opsin

7 Child Features

DB identifier Type Name
IPR002206 Family Opsin, pineal type
IPR000378 Family Opsin red/green sensitive
IPR000732 Family Rhodopsin
IPR000856 Family Opsin RH3/RH4
IPR001391 Family Opsin lateral eye type
IPR001521 Family Opsin, blue sensitive
IPR001735 Family Opsin RH1/RH2

0 Contains

1 Cross References

Identifier
PR00238

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0007186 IPR001760
GO:0007601 IPR001760
GO:0016021 IPR001760

3 Ontology Annotations

GO Term Gene Name
GO:0007186 IPR001760
GO:0007601 IPR001760
GO:0016021 IPR001760

1 Parent Features

DB identifier Type Name
IPR000276 Family G protein-coupled receptor, rhodopsin-like

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            7947717
            1663559
            3303660