3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0003677 | IPR002297 |
GO:0006260 | IPR002297 |
GO:0005760 | IPR002297 |
Type: | Family | Name: | DNA-directed DNA-polymerase, family A, mitochondria |
Description: | DNA carries the biological information that instructs cells how to exist in an ordered fashion. Accurate replication is thus one of the mostimportant events in the cell life cycle. This function is mediated by DNA-directed DNA-polymerases, which add nucleotide triphosphate (dNTP)residues to the 5'-end of the growing DNA chain, using a complementary DNA as template. Small RNA molecules are generally used as primers forchain elongation, although terminal proteins may also be used.DNA-dependent DNA-polymerases have been grouped into families, denoted A, B and X, on the basis of sequence similarities [, ]. Members of family A, which includes bacterial and bacteriophage polymerases, share significant similarity to Escherichia colipolymerase I; hence family A is also known as the pol I family. The bacterial polymerases also contain an exonuclease activity, which is coded for in the N-terminal portion. The yeast gamma polymerases show some similarity to the prokaryotic nuclear polymerases of family A, but their function is restricted to mitochondrial DNA replication and repair []. | Short Name: | DNA-dir_DNA_pol_A_mt |
GO Term | Gene Name |
---|---|
GO:0003677 | IPR002297 |
GO:0006260 | IPR002297 |
GO:0005760 | IPR002297 |