Protein Domain : IPR008341

Type:  Family Name:  Dishevelled-2
Description:  Dishevelled (Dsh) proteins possess three conserved domains: an amino-terminal DIX domain, a central PDZ and a carboxyl-terminal DEP domain. They acts downstream of Fz receptors in the Wnt signalling pathway, which controls a variety of developmental and homeostatic events []. Dishevelled-2 (DVL-2) participates in Wnt signalling by binding to the cytoplasmic C terminus of frizzled family members and transducing the Wnt signal to down-stream effectors []. Short Name:  DVL2
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0 Child Features

5 Contains

DB identifier Type Name
IPR011991 Domain Winged helix-turn-helix DNA-binding domain
IPR001478 Domain PDZ domain
IPR000591 Domain DEP domain
IPR001158 Domain DIX domain
IPR003351 Domain Dishevelled protein domain

2 Cross Referencess

Identifier
PTHR10878:SF8
PR01762

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0016055 IPR008341

1 Ontology Annotations

GO Term Gene Name
GO:0016055 IPR008341

1 Parent Features

DB identifier Type Name
IPR008339 Family Dishevelled family

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15353129
            19252499