Protein Domain : IPR000633

Type:  Conserved_site Name:  Vinculin, conserved site
Description:  Vinculin is a eukaryotic protein that appears to be involved in the attachment of actin-based microfilaments to the plasma membrane []. It also interacts with other structural proteins, such as talin [] and alpha-actinin. The protein is located on the cytoplasmic side of focal contacts or adhesion plaques. Vinculinis a large protein (~1000 residues) that contains an acidic N-terminal domain, separated from a smaller, basic C-terminal domain by a 50-residue proline-rich region []. The central part of the N-terminal domainconsists of a variable number of repeats of a 110-residue domain, one of which is lacking in nematode vinculin []. Short Name:  Vinculin_CS

0 Child Features

0 Contains

2 Cross Referencess

Identifier
PS00663
PS00664

2 Found Ins

DB identifier Type Name
IPR006077 Family Vinculin/alpha-catenin
IPR001033 Family Alpha-catenin

3 GO Annotations

GO Term Gene Name
GO:0005198 IPR000633
GO:0007155 IPR000633
GO:0015629 IPR000633

3 Ontology Annotations

GO Term Gene Name
GO:0005198 IPR000633
GO:0007155 IPR000633
GO:0015629 IPR000633

0 Parent Features

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            2112986
            2512301
            2116004
            1924379