Protein Domain : IPR012691

Type:  Family Name:  2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase variant
Description:  This entry represents a subset of the DapA (dihydrodipicolinate synthase) family which has apparently evolved a separate function. The product of DapA, dihydrodipicolinate, results from the non-enzymatic cyclization and dehydration of 6-amino-2,4-dihydroxyhept-2-ene-1,7-dioic acid, which is different from the substrate of this reaction only in the presence of the amino group. In the absence of this amino group, and running the reaction in the opposite direction, the reaction corresponds to the HpaI aldolase component of the 4-hydroxyphenylacetic acid catabolism pathway (see ). At present, this variant of DapA is found only in Oceanobacillus iheyensis HTE831and Thermus thermophilus(strain HB27/ATCC BAA-163/DSM 7039). In both of these cases, one or more other DapA genes can be found and the members of this family are found in the operon for 4-hydroxyphenylacetic acid catabolism. Short Name:  HpaI_NOT_DapA
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0 Child Features

1 Contains

DB identifier Type Name
IPR020625 Active_site Schiff base-forming aldolase, active site

1 Cross References

Identifier
TIGR02313

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0008840 IPR012691
GO:0019877 IPR012691
GO:0005737 IPR012691

3 Ontology Annotations

GO Term Gene Name
GO:0008840 IPR012691
GO:0019877 IPR012691
GO:0005737 IPR012691

1 Parent Features

DB identifier Type Name
IPR005263 Family 4-hydroxy-tetrahydrodipicolinate synthase, DapA

0 Proteins

0 Publications