1 Child Features
| DB identifier | Type | Name |
|---|---|---|
| IPR009220 | Family | Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein |
| Type: | Family | Name: | tRNA N6-adenosine threonylcarbamoyltransferase, Kae1 |
| Description: | This family represents Kae1 homologues from Archaea. Its partner kinase Bud32 is fused with it in about half of the known archaeal genomes []. The pair, which appears universal in the archaea, corresponds to EKC/KEOPS complex in eukaryotes []. Kae1 homologues are thought to be required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. A recent characterisation of the member from Pyrococcus abyssi, as an iron-binding, atypical DNA-binding protein with an apurinic lyase activity, challenges the previous annotation of these proteins as O-sialoglycoprotein endopeptidases []. | Short Name: | Kae1 |
| DB identifier | Type | Name |
|---|---|---|
| IPR009220 | Family | Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein |
