Protein Domain : IPR017197

Type:  Family Name:  Bone morphogenetic protein 3/3B
Description:  This group includes two members of the TGF-beta superfamily: bone morphogenetic protein 3 (BMP3) and bone morphogenetic protein 3B (BMP3B), also known as growth differentiation factor 10 (GDF10). Together they represent a subgroup of the BMP family. They are involved in development and organogenesis. In developing embryos, they have different dorsalising activities []. BMP3 is a negative regulator of bone density []. BMP3B plays an inhibitory role in the process of osteoblast differentiation []. Short Name:  BMP3/BMP3B
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0 Child Features

2 Contains

DB identifier Type Name
IPR001839 Domain Transforming growth factor-beta, C-terminal
IPR017948 Conserved_site Transforming growth factor beta, conserved site

1 Cross References

Identifier
PIRSF037403

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0001649 IPR017197

1 Ontology Annotations

GO Term Gene Name
GO:0001649 IPR017197

1 Parent Features

DB identifier Type Name
IPR015615 Family Transforming growth factor-beta-related

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11138004
            22155034
            14977563