4 GO Annotations
| GO Term | Gene Name |
|---|---|
| GO:0003723 | IPR019770 |
| GO:0003743 | IPR019770 |
| GO:0006413 | IPR019770 |
| GO:0005737 | IPR019770 |
4 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0003723 | IPR019770 |
| GO:0003743 | IPR019770 |
| GO:0006413 | IPR019770 |
| GO:0005737 | IPR019770 |
| Type: | Conserved_site | Name: | Eukaryotic translation initiation factor 4E (eIF-4E), conserved site |
| Description: | Eukaryotic translation initiation factor 4E (eIF-4E) [] is a protein thatbinds to the cap structure of eukaryotic cellular mRNAs. eIF-4E recognises and binds the 7-methylguanosine-containing (m7Gppp) cap during an early step in the initiationof protein synthesis and facilitates ribosome binding to a mRNA by inducing the unwinding of its secondary structures. eIF-4E is a conserved protein of about 25 kDa. Site directed mutagenesis experiments have shown [] that a tryptophan in the central part of the sequence of human eIF-4E seems to be implicated in cap-binding. The signature pattern used in this entry includes this tryptophan. | Short Name: | TIF_eIF_4E_CS |
| GO Term | Gene Name |
|---|---|
| GO:0003723 | IPR019770 |
| GO:0003743 | IPR019770 |
| GO:0006413 | IPR019770 |
| GO:0005737 | IPR019770 |
| GO Term | Gene Name |
|---|---|
| GO:0003723 | IPR019770 |
| GO:0003743 | IPR019770 |
| GO:0006413 | IPR019770 |
| GO:0005737 | IPR019770 |
