Protein Domain : IPR001040

Type:  Family Name:  Translation Initiation factor eIF- 4e
Description:  Eukaryotic translation initiation factor 4E (eIF-4E) [] is a protein thatbinds to the cap structure of eukaryotic cellular mRNAs. eIF-4E recognises and binds the 7-methylguanosine-containing (m7Gppp) cap during an early step in the initiationof protein synthesis and facilitates ribosome binding to a mRNA by inducing the unwinding of its secondary structures. A tryptophan in the central part of the sequence of humaneIF-4E seems to be implicated in cap-binding []. Short Name:  TIF_eIF_4E
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0 Child Features

1 Contains

DB identifier Type Name
IPR019770 Conserved_site Eukaryotic translation initiation factor 4E (eIF-4E), conserved site

2 Cross Referencess

Identifier
PTHR11960
PF01652

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0003723 IPR001040
GO:0003743 IPR001040
GO:0006413 IPR001040
GO:0005737 IPR001040

4 Ontology Annotations

GO Term Gene Name
GO:0003723 IPR001040
GO:0003743 IPR001040
GO:0006413 IPR001040
GO:0005737 IPR001040

1 Parent Features

DB identifier Type Name
IPR023398 Family Translation Initiation factor eIF- 4e-like

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
419389 D8S8S9 PAC:15408974 Selaginella moellendorffii 209  
119068 D8SJX5 PAC:15408394 Selaginella moellendorffii 203  
38791 D8SQ36 PAC:15417512 Selaginella moellendorffii 77  
129372 D8T0L9 PAC:15417966 Selaginella moellendorffii 124  
125743 D8SVJ0 PAC:15409283 Selaginella moellendorffii 139  
evm.model.supercontig_17.108 PAC:16410598 Carica papaya 77  
evm.model.supercontig_44.11 PAC:16420113 Carica papaya 206  
evm.model.supercontig_51.133 PAC:16421799 Carica papaya 230  
29693.m002098 B9S1A2 PAC:16806068 Ricinus communis 234  
29950.m001122 B9SHE9 PAC:16814398 Ricinus communis 222  
30008.m000821 B9SQU9 PAC:16815591 Ricinus communis 201  
Cucsa.383360.1 B0F832 PAC:16982358 Cucumis sativus 203  
Cucsa.383360.2 PAC:16982359 Cucumis sativus 148  
Cucsa.212630.1 PAC:16969370 Cucumis sativus 239  
Cucsa.212630.2 B0F6T5 PAC:16969371 Cucumis sativus 235  
orange1.1g027346m A0A067GE56 PAC:18112408 Citrus sinensis 224  
orange1.1g029621m A0A067GH59 PAC:18112409 Citrus sinensis 190  
orange1.1g030132m A0A067GRQ0 PAC:18112410 Citrus sinensis 182  
orange1.1g032034m A0A067GEG1 PAC:18112411 Citrus sinensis 148  
orange1.1g030198m A0A067EIJ2 PAC:18116209 Citrus sinensis 181  
orange1.1g031207m A0A067EM83 PAC:18116210 Citrus sinensis 164  
orange1.1g029174m A0A067EJP3 PAC:18130166 Citrus sinensis 197  
AT4G18040.1 O23252 PAC:19645429 Arabidopsis thaliana 235  
AT5G18110.1 Q9FK59 PAC:19667959 Arabidopsis thaliana 221  
AT5G35620.2 O04663 PAC:19671806 Arabidopsis thaliana 167  
AT5G35620.1 O04663 PAC:19671805 Arabidopsis thaliana 198  
AT1G29550.1 Q9C7P6 PAC:19657774 Arabidopsis thaliana 240  
AT1G29590.2 PAC:19651097 Arabidopsis thaliana 300  
AT1G29590.1 PAC:19651098 Arabidopsis thaliana 285  
Thhalv10026131m V4P7P3 PAC:20193525 Eutrema salsugineum 235  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1733496
            1672854