3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0005149 | IPR027169 |
| GO:0006954 | IPR027169 |
| GO:0006955 | IPR027169 |
1 Parent Features
| DB identifier | Type | Name |
|---|---|---|
| IPR003297 | Family | Interleukin-1 receptor antagonist / Interleukin-36 |
| Type: | Family | Name: | Interleukin-37 |
| Description: | Interleukin-36 cytokines constitute a novel cluster of cytokines with structural and functional similarities to IL-1 []. Previously designated as interleukin-1 family members 5 - 10 (IL-1F5 to IL-1F10), they have recently been reclassified according to an updated cytokine nomenclature scheme []. Family members include:interleukin-36 alpha, beta and gamma (previously IL-1F6, IL-1F8 and IL-1F9, respectively), which are pro-inflammatory and signal through IL-1Rrp2 and IL-1RAcP []. interleukin-36 receptor antagonist (previously IL-1F5), which binds IL-1Rrp2, acting as an antagonist for interleukins signalling via this route [].interleukin-37 (IL-1F7), which exerts anti-inflammatory actions by suppressing production of pro-inflammatory cytokines [].IL-1F10, whose function is unknown. This entry represents interleukin-37. | Short Name: | IL-37 |
| GO Term | Gene Name |
|---|---|
| GO:0005149 | IPR027169 |
| GO:0006954 | IPR027169 |
| GO:0006955 | IPR027169 |
| DB identifier | Type | Name |
|---|---|---|
| IPR003297 | Family | Interleukin-1 receptor antagonist / Interleukin-36 |
