Protein Domain : IPR005768

Type:  Family Name:  Lysine-arginine-ornithine-binding periplasmic protein
Description:  Bacterial high affinity transport systems are involved in active transport of solutes across the cytoplasmic membrane. The protein components of these traffic systems include one or two transmembrane protein components, one or two membrane-associated ATP-binding proteins (ABC transporters; see ) and a high affinity periplasmic solute-binding protein. The later are thought to bind the substrate in the vicinity of the inner membrane, and to transfer it to a complex of inner membrane proteins for concentration into the cytoplasm. In Gram-positive bacteria which are surrounded by a single membrane and have therefore no periplasmic region the equivalent proteins are bound to the membrane via an N-terminal lipid anchor. These homologue proteins do not play an integral role in the transport process per se, but probably serve as receptors to trigger or initiate translocation of the solute through the membrane by binding to external sites of the integral membrane proteins of the efflux system. In addition at least some solute-binding proteins function in the initiation of sensory transduction pathways.On the basis of sequence similarities, the vast majority of these solute-binding proteins can be grouped into eight families of clusters, which generally correlate with the nature of the solute bound. Family 3 groups together specific amino acids and opine-binding periplasmic proteins and a periplasmic homologue with catalytic activity. Short Name:  Lys_Arg_Orn-bd

0 Child Features

1 Contains

DB identifier Type Name
IPR018313 Conserved_site Solute-binding protein family 3, conserved site

1 Cross References

Identifier
TIGR01096

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0005215 IPR005768
GO:0006810 IPR005768
GO:0030288 IPR005768

3 Ontology Annotations

GO Term Gene Name
GO:0005215 IPR005768
GO:0006810 IPR005768
GO:0030288 IPR005768

0 Parent Features

0 Proteins

0 Publications