Protein Domain : IPR029924

Type:  Family Name:  Destrin
Description:  Destrin (Dstn) is an actin depolymerising factor that maintains a homeostatic ratio of actin in two forms, filamentous actin (F-actin) and globular actin (G-actin). It severs actin filaments (F-actin) and binds to actin monomers (G-actin). Mutations in Destrin gene lead to abnormalities in the structure and function of the cornea and subsequent blindness in mice [, ]. Short Name:  Dstn
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR11913:SF18

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0030836 IPR029924
GO:0051014 IPR029924
GO:0015629 IPR029924

3 Ontology Annotations

GO Term Gene Name
GO:0030836 IPR029924
GO:0051014 IPR029924
GO:0015629 IPR029924

1 Parent Features

DB identifier Type Name
IPR017904 Family ADF/Cofilin/Destrin

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12700171
            22419854