4 GO Annotations
| GO Term | Gene Name |
|---|---|
| GO:0008424 | IPR015827 |
| GO:0033578 | IPR015827 |
| GO:0016021 | IPR015827 |
| GO:0032580 | IPR015827 |
4 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0008424 | IPR015827 |
| GO:0033578 | IPR015827 |
| GO:0016021 | IPR015827 |
| GO:0032580 | IPR015827 |
| Type: | Family | Name: | Alpha-(1,6)-fucosyltransferase, eukaryotic type |
| Description: | Members of this group have enzymatic activity . They transfer fucose on glycoproteins to the innermost asparagine-linked N-acetylglucosamine of the chitobiose disaccharide-core unit []. Core alpha 1,6-fucosylation is a conserved feature of animal N-linked oligosaccharides, being present in both invertebrates and vertebrates [].All known fucosyltransferases are type II transmembrane proteins with four distinct domains: cytoplasmic, transmembrane, hypervariable, and catalytic. The catalytic domain resides in the luminal side of the trans-Golgi compartment []. Members of this group share the conserved three alpha-6-motifs that are also present in the bacterial 6-alpha fucosyltransferases () [].Disruption of the 6-alpha fucosyltransferase gene from a Chinese hamster ovary cell line has been shown to produce completely defucosylated recombinant antibodies [].All members contain an SH3 domain () near the carboxyl end, but its function is unknown. | Short Name: | Alpha1_6FUT_euk |
| GO Term | Gene Name |
|---|---|
| GO:0008424 | IPR015827 |
| GO:0033578 | IPR015827 |
| GO:0016021 | IPR015827 |
| GO:0032580 | IPR015827 |
| GO Term | Gene Name |
|---|---|
| GO:0008424 | IPR015827 |
| GO:0033578 | IPR015827 |
| GO:0016021 | IPR015827 |
| GO:0032580 | IPR015827 |
