GO Term : GO:0004693 cyclin-dependent protein serine/threonine kinase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

1 Ontology Annotations

GO Term Gene Name
GO:0004693 IPR028788

34 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0005515 protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0004672 protein kinase activity Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
GO:0006468 protein phosphorylation The process of introducing a phosphate group on to a protein.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0016310 phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
GO:0016772 transferase activity, transferring phosphorus-containing groups Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0006796 phosphate-containing compound metabolic process The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0051726 regulation of cell cycle Any process that modulates the rate or extent of progression through the cell cycle.
GO:0016301 kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0016773 phosphotransferase activity, alcohol group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).
GO:0019538 protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0004674 protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
GO:0006464 cellular protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0043412 macromolecule modification The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0044267 cellular protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0006793 phosphorus metabolic process The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

59 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
regulates GO:0004693 GO:0000079
regulates GO:0004693 GO:0000079
is_a GO:0097472 GO:0004693
is_a GO:0004674 GO:0004693
part of GO:0050794 GO:0004693
is_a GO:0016740 GO:0004693
is_a GO:0016301 GO:0004693
part of GO:0051726 GO:0004693
part of GO:0036211 GO:0004693
has_part GO:0005515 GO:0004693
part of GO:0019538 GO:0004693
is_a GO:0003824 GO:0004693
has_part GO:0003674 GO:0004693
part of GO:0043412 GO:0004693
part of GO:0006464 GO:0004693
part of GO:0065007 GO:0004693
has_part GO:0030332 GO:0004693
part of GO:0006468 GO:0004693
is_a GO:0004672 GO:0004693
part of GO:0044260 GO:0004693
part of GO:0043170 GO:0004693
part of GO:0044267 GO:0004693
has_part GO:0005488 GO:0004693
is_a GO:0016773 GO:0004693
part of GO:0071704 GO:0004693
part of GO:0050789 GO:0004693
part of GO:0008150 GO:0004693
is_a GO:0016772 GO:0004693
part of GO:0008152 GO:0004693
is_a GO:0003674 GO:0004693

20 Synonyms

Name Type
CDK, catalytic subunit activity synonym
CDK activity synonym
cyclin D-cdk6 kinase activity synonym
Cdk-activating protein kinase activity synonym
cdk-activating kinase activity synonym
cyclin E kinase activity synonym
cyclin D-dependent kinase activity synonym
cyclin-dependent kinase 6 activity synonym
cyclin-A associated kinase activity synonym
cyclin-dependent kinase-2 activity synonym
cyclin-dependent kinase activity synonym
cyclin-dependent protein kinase activity synonym
cyclin-dependent kinase-4 activity synonym
D-type cyclin kinase activity synonym
cyclin-dependent protein kinase, intrinsic catalyst activity synonym
GO:0016537 alt_id
neuronal cdc2-like kinase activity synonym
ATP:cyclin phosphotransferase activity synonym
CDK synonym
cdc2 kinase activity synonym