GO Term : GO:1902532 negative regulation of intracellular signal transduction GO
Namespace:  biological_process Obsolete:  false
description  Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

26 Parents

Identifier Name Description
GO:0007165 signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0035556 intracellular signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
GO:0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of signal transduction.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0007154 cell communication Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0023052 signaling The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
GO:0044700 single organism signaling A signaling process occurring within a single organism.
GO:0023051 regulation of signaling Any process that modulates the frequency, rate or extent of a signaling process.
GO:1902531 regulation of intracellular signal transduction Any process that modulates the frequency, rate or extent of intracellular signal transduction.
GO:0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GO:0010646 regulation of cell communication Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0009968 negative regulation of signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.
GO:0023057 negative regulation of signaling Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process.
GO:0048585 negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GO:1902532 negative regulation of intracellular signal transduction Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.
GO:0010648 negative regulation of cell communication Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

163 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:1902532 GO:0000173
is_a GO:1902532 GO:0000188
is_a GO:1902532 GO:0000200
has_part GO:1902532 GO:0007193
has_part GO:1902532 GO:0007195
has_part GO:1902532 GO:0007196
has_part GO:1902532 GO:0007197
has_part GO:1902532 GO:0007198
is_a GO:1902532 GO:0007253
part of GO:1902532 GO:0007253
negatively regulates GO:1902532 GO:0008588
is_a GO:1902532 GO:0010105
is_a GO:1902532 GO:0010751
is_a GO:1902532 GO:0010754
is_a GO:1902532 GO:0014067
part of GO:1902532 GO:0017017
is_a GO:1902532 GO:0031030
is_a GO:1902532 GO:0031586
has_part GO:1902532 GO:0031635
is_a GO:1902532 GO:0032007
is_a GO:1902532 GO:0032013
is_a GO:1902532 GO:0032016
is_a GO:1902532 GO:0032873
part of GO:1902532 GO:0033549
part of GO:1902532 GO:0033550
is_a GO:1902532 GO:0035021
is_a GO:1902532 GO:0035024
is_a GO:1902532 GO:0035331
is_a GO:1902532 GO:0035423
part of GO:1902532 GO:0038069

36 Synonyms

Name Type
negative regulation of intracellular signaling chain synonym
negative regulation of intracellular signaling cascade synonym
negative regulation of signal transduction via intracellular signaling cascade synonym
negative regulation of intracellular signaling pathway synonym
GO:0010741 alt_id
negative regulation of signal transmission via intracellular cascade synonym
down regulation of intracellular signal transduction pathway synonym
down regulation of intracellular signal transduction synonym
down regulation of intracellular signaling chain synonym
down regulation of intracellular signaling cascade synonym
down regulation of signal transduction via intracellular signaling cascade synonym
down regulation of intracellular signaling pathway synonym
down-regulation of intracellular signal transduction synonym
down regulation of signal transmission via intracellular cascade synonym
down-regulation of intracellular signaling cascade synonym
down-regulation of intracellular signal transduction pathway synonym
down-regulation of intracellular signaling pathway synonym
down-regulation of intracellular signaling chain synonym
down-regulation of signal transmission via intracellular cascade synonym
down-regulation of signal transduction via intracellular signaling cascade synonym
downregulation of intracellular signal transduction pathway synonym
downregulation of intracellular signal transduction synonym
downregulation of intracellular signaling chain synonym
downregulation of intracellular signaling cascade synonym
downregulation of signal transduction via intracellular signaling cascade synonym
downregulation of intracellular signaling pathway synonym
inhibition of intracellular signal transduction synonym
downregulation of signal transmission via intracellular cascade synonym
inhibition of intracellular signaling cascade synonym
inhibition of intracellular signal transduction pathway synonym