GO Term : GO:0045259 proton-transporting ATP synthase complex GO

Namespace:  cellular_component Obsolete:  false
description  A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP during oxidative phosphorylation. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism; the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits and the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

12 Parents

Identifier Name Description
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0016469 proton-transporting two-sector ATPase complex A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0098796 membrane protein complex Any protein complex that is part of a membrane.
GO:0044425 membrane part Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0045259 proton-transporting ATP synthase complex A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP during oxidative phosphorylation. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism; the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits and the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient.

36 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0045259 GO:0000274
part of GO:0045259 GO:0000275
part of GO:0045259 GO:0000276
is_a GO:0045259 GO:0005753
is_a GO:0045259 GO:0005753
part of GO:0045259 GO:0005754
part of GO:0045259 GO:0005756
part of GO:0045259 GO:0033174
part of GO:0045259 GO:0033175
is_a GO:0016469 GO:0045259
is_a GO:0044424 GO:0045259
is_a GO:0098796 GO:0045259
is_a GO:0044425 GO:0045259
part of GO:0044464 GO:0045259
is_a GO:0043234 GO:0045259
part of GO:0005575 GO:0045259
part of GO:0016020 GO:0045259
is_a GO:0005575 GO:0045259
part of GO:0005622 GO:0045259
part of GO:0005623 GO:0045259
is_a GO:0032991 GO:0045259
is_a GO:0044464 GO:0045259
is_a GO:0045259 GO:0045260
is_a GO:0045259 GO:0045260
part of GO:0045259 GO:0045261
part of GO:0045259 GO:0045262
part of GO:0045259 GO:0045263
part of GO:0045259 GO:0045264
part of GO:0045259 GO:0045265
part of GO:0045259 GO:0045266

4 Synonyms

Name Type
hydrogen-translocating F-type ATPase complex synonym
proton-transporting F-type ATPase complex synonym
GO:0045255 alt_id
hydrogen-transporting ATP synthase complex synonym