GO Term : GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

10 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds Catalysis of the hydrolysis of any N-glycosyl bond.
GO:0016798 hydrolase activity, acting on glycosyl bonds Catalysis of the hydrolysis of any glycosyl bond.
GO:0019104 DNA N-glycosylase activity Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0000700 mismatch base pair DNA N-glycosylase activity Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.

9 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0000700 GO:0000701
part of GO:0008152 GO:0000701
is_a GO:0003824 GO:0000701
part of GO:0008150 GO:0000701
is_a GO:0019104 GO:0000701
is_a GO:0016798 GO:0000701
is_a GO:0016787 GO:0000701
is_a GO:0003674 GO:0000701
is_a GO:0016799 GO:0000701

1 Synonyms

Name Type
A/G-specific adenine DNA glycosylase activity synonym