GO:0003824
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catalytic activity
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Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
GO:0016787
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hydrolase activity
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Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. |
GO:0005515
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protein binding
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Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
GO:0005488
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binding
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The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
GO:0008152
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metabolic process
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The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. |
GO:0016311
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dephosphorylation
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The process of removing one or more phosphoric (ester or anhydride) residues from a molecule. |
GO:0016791
|
phosphatase activity
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Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. |
GO:0006796
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phosphate-containing compound metabolic process
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The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. |
GO:0044237
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cellular metabolic process
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The chemical reactions and pathways by which individual cells transform chemical substances. |
GO:0016788
|
hydrolase activity, acting on ester bonds
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Catalysis of the hydrolysis of any ester bond. |
GO:0042578
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phosphoric ester hydrolase activity
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Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3. |
GO:0004857
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enzyme inhibitor activity
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Binds to and stops, prevents or reduces the activity of an enzyme. |
GO:0030234
|
enzyme regulator activity
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Binds to and modulates the activity of an enzyme. |
GO:0050790
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regulation of catalytic activity
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Any process that modulates the activity of an enzyme. |
GO:0043086
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negative regulation of catalytic activity
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Any process that stops or reduces the activity of an enzyme. |
GO:0009987
|
cellular process
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Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
GO:0006793
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phosphorus metabolic process
|
The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4). |
GO:0008150
|
biological_process
|
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
GO:0003674
|
molecular_function
|
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. |
GO:0065007
|
biological regulation
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Any process that modulates a measurable attribute of any biological process, quality or function. |
GO:0050789
|
regulation of biological process
|
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. |
GO:0019222
|
regulation of metabolic process
|
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. |
GO:0065009
|
regulation of molecular function
|
Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. |
GO:0009892
|
negative regulation of metabolic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. |
GO:0048519
|
negative regulation of biological process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. |
GO:0044092
|
negative regulation of molecular function
|
Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. |
GO:0098772
|
molecular function regulator
|
A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators. |
GO:0019899
|
enzyme binding
|
Interacting selectively and non-covalently with any enzyme. |
GO:0019212
|
phosphatase inhibitor activity
|
Stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule. |
GO:0001691
|
pseudophosphatase activity
|
Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues. |