GO Term : GO:0002295 T-helper cell lineage commitment GO

Namespace:  biological_process Obsolete:  false
description  The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

59 Parents

Identifier Name Description
GO:0007275 multicellular organismal development The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GO:0006955 immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
GO:0032502 developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
GO:0030154 cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
GO:0048513 organ development Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GO:0007155 cell adhesion The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
GO:0030097 hemopoiesis The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0044707 single-multicellular organism process A biological process occurring within a single, multicellular organism.
GO:0032501 multicellular organismal process Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
GO:0044767 single-organism developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, involving only one organism.
GO:0048856 anatomical structure development The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
GO:0048869 cellular developmental process A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
GO:0045165 cell fate commitment The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
GO:0098609 cell-cell adhesion The attachment of one cell to another cell via adhesion molecules.
GO:0022610 biological adhesion The attachment of a cell or organism to a substrate or other organism.
GO:0048731 system development The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
GO:0046649 lymphocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
GO:0045321 leukocyte activation A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
GO:0001775 cell activation A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0042110 T cell activation The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0016337 single organismal cell-cell adhesion The attachment of one cell to another cell via adhesion molecules, where both cells are part of the same organism.
GO:0070489 T cell aggregation The adhesion of one T cell to one or more other T cells via adhesion molecules.
GO:0070486 leukocyte aggregation The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules.
GO:0098602 single organism cell adhesion The attachment, via cell adhesion molecules, of a cell to either another cell of the same organism, or to an underlying substrate of the same organism such as the extracellular matrix.

73 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0043373 GO:0002295
part of GO:0042093 GO:0002295
part of GO:0006955 GO:0002295
part of GO:0048513 GO:0002295
part of GO:0045321 GO:0002295
part of GO:0034109 GO:0002295
part of GO:0046649 GO:0002295
is_a GO:0045165 GO:0002295
part of GO:0098609 GO:0002295
part of GO:0030154 GO:0002295
part of GO:0048869 GO:0002295
is_a GO:0009987 GO:0002295
part of GO:0098602 GO:0002295
part of GO:0044707 GO:0002295
part of GO:0002521 GO:0002295
part of GO:0002366 GO:0002295
part of GO:0002520 GO:0002295
part of GO:0002286 GO:0002295
part of GO:0002285 GO:0002295
part of GO:0002287 GO:0002295
part of GO:0044763 GO:0002295
part of GO:0045058 GO:0002295
part of GO:0009987 GO:0002295
is_a GO:0048869 GO:0002295
part of GO:0071593 GO:0002295
part of GO:0032502 GO:0002295
part of GO:0048731 GO:0002295
part of GO:0002252 GO:0002295
part of GO:0048534 GO:0002295
part of GO:0032501 GO:0002295

3 Synonyms

Name Type
T-helper cell fate commitment synonym
Th0 lineage commitment synonym
Thp lineage commitment synonym