GO Term : GO:0003863 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

11 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide.
GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0003863 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2.

10 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016624 GO:0003863
part of GO:0044710 GO:0003863
part of GO:0044699 GO:0003863
part of GO:0055114 GO:0003863
is_a GO:0003674 GO:0003863
part of GO:0008150 GO:0003863
part of GO:0008152 GO:0003863
is_a GO:0016491 GO:0003863
is_a GO:0016903 GO:0003863
is_a GO:0003824 GO:0003863

23 Synonyms

Name Type
BCOAD activity synonym
BCKDH activity synonym
branched-chain (-2-oxoacid) dehydrogenase (BCD) activity synonym
branched chain keto acid dehydrogenase activity synonym
branched-chain 2-oxo acid dehydrogenase activity synonym
branched-chain 2-keto acid dehydrogenase activity synonym
branched-chain alpha-oxo acid dehydrogenase activity synonym
branched-chain alpha-keto acid dehydrogenase activity synonym
branched-chain ketoacid dehydrogenase activity synonym
branched-chain keto acid dehydrogenase activity synonym
dehydrogenase, branched chain alpha-keto acid activity synonym
dehydrogenase, 2-oxoisovalerate (lipoate) activity synonym
2-oxoisocaproate dehydrogenase activity synonym
3-methyl-2-oxobutanoate dehydrogenase (lipoamide) activity synonym
2-oxoisovalerate (lipoate) dehydrogenase activity synonym
3-methyl-2-oxobutanoate:lipoamide oxidoreductase (decarboxylating and acceptor-2-methylpropanoylating) activity synonym
3-methyl-2-oxobutanoate:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating) synonym
alpha-ketoisocaproate dehydrogenase activity synonym
alpha-keto-alpha-methylvalerate dehydrogenase activity synonym
alpha-ketoisocaproic-alpha-keto-alpha-methylvaleric dehydrogenase activity synonym
alpha-ketoisocaproic dehydrogenase activity synonym
alpha-oxoisocaproate dehydrogenase activity synonym
alpha-ketoisovalerate dehydrogenase activity synonym