GO Term : GO:0003886 DNA (cytosine-5-)-methyltransferase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

1 Ontology Annotations

GO Term Gene Name
GO:0003886 IPR017198

39 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0008168 methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0010468 regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0006306 DNA methylation The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006259 DNA metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO:0043412 macromolecule modification The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
GO:0032259 methylation The process in which a methyl group is covalently attached to a molecule.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0006304 DNA modification The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0040029 regulation of gene expression, epigenetic Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0090304 nucleic acid metabolic process Any cellular metabolic process involving nucleic acids.
GO:0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:1901360 organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound.
GO:0046483 heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

41 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0090116 GO:0003886
is_a GO:0009008 GO:0003886
is_a GO:0008757 GO:0003886
part of GO:0009987 GO:0003886
is_a GO:0016741 GO:0003886
is_a GO:0016740 GO:0003886
part of GO:0090304 GO:0003886
is_a GO:0003824 GO:0003886
part of GO:0034641 GO:0003886
part of GO:0006807 GO:0003886
part of GO:0044728 GO:0003886
part of GO:0040029 GO:0003886
part of GO:0006725 GO:0003886
part of GO:0065007 GO:0003886
part of GO:0006306 GO:0003886
part of GO:0006305 GO:0003886
part of GO:0060255 GO:0003886
part of GO:0043414 GO:0003886
part of GO:0006304 GO:0003886
part of GO:0043412 GO:0003886
part of GO:0032776 GO:0003886
part of GO:0032259 GO:0003886
part of GO:0010468 GO:0003886
part of GO:0046483 GO:0003886
part of GO:0044260 GO:0003886
part of GO:1901360 GO:0003886
part of GO:0043170 GO:0003886
part of GO:0050789 GO:0003886
part of GO:0071704 GO:0003886
part of GO:0019222 GO:0003886

20 Synonyms

Name Type
modification methylase activity synonym
restriction-modification system activity synonym
cytosine 5-methyltransferase activity synonym
cytosine DNA methyltransferase activity synonym
cytosine DNA methylase activity synonym
deoxyribonucleic (cytosine-5-)-methyltransferase activity synonym
cytosine-specific DNA methyltransferase activity synonym
deoxyribonucleic methylase activity synonym
deoxyribonucleic acid (cytosine-5-)-methyltransferase activity synonym
DNA cytosine C(5) methylase activity synonym
DNA 5-cytosine methylase activity synonym
DNA cytosine methylase activity synonym
DNA cytosine C5 methylase activity synonym
DNA-cytosine methyltransferase activity synonym
DNA-cytosine 5-methylase activity synonym
S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase activity synonym
methylphosphotriester-DNA methyltransferase activity synonym
type II DNA methylase activity synonym
site-specific DNA-methyltransferase (cytosine-specific) activity synonym
GO:0008326 alt_id