GO Term : GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity GO

Namespace:  molecular_function Obsolete:  false
description  Enables the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

1 Ontology Annotations

GO Term Gene Name
GO:0005220 IPR000493

71 Parents

Identifier Name Description
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0055085 transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0006812 cation transport The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0007165 signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0022857 transmembrane transporter activity Enables the transfer of a substance from one side of a membrane to the other.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GO:0022891 substrate-specific transmembrane transporter activity Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
GO:0005216 ion channel activity Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
GO:0006811 ion transport The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0030001 metal ion transport The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0004871 signal transducer activity Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
GO:0034220 ion transmembrane transport A process in which an ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0008324 cation transmembrane transporter activity Enables the transfer of cation from one side of the membrane to the other.
GO:0015075 ion transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other.
GO:0035556 intracellular signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
GO:0046873 metal ion transmembrane transporter activity Enables the transfer of metal ions from one side of a membrane to the other.
GO:0070588 calcium ion transmembrane transport A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0015267 channel activity Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
GO:0004872 receptor activity Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
GO:0006816 calcium ion transport The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0005262 calcium channel activity Enables the selective, facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0036094 small molecule binding Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule.
GO:0005261 cation channel activity Enables the selective, energy-independent passage of cations across a lipid bilayer down a concentration gradient.
GO:0015085 calcium ion transmembrane transporter activity Enables the transfer of calcium (Ca) ions from one side of a membrane to the other.
GO:0098655 cation transmembrane transport A process in which a cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0007154 cell communication Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

79 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0015278 GO:0005220
is_a GO:0005057 GO:0005220
is_a GO:0005217 GO:0005220
has_part GO:0070679 GO:0005220
part of GO:0048016 GO:0005220
is_a GO:0038023 GO:0005220
part of GO:0050896 GO:0005220
part of GO:0006816 GO:0005220
part of GO:0070588 GO:0005220
part of GO:0019932 GO:0005220
part of GO:0007154 GO:0005220
has_part GO:0036094 GO:0005220
part of GO:1902578 GO:0005220
part of GO:0044765 GO:0005220
is_a GO:0046873 GO:0005220
is_a GO:0004872 GO:0005220
is_a GO:0004871 GO:0005220
occurs in GO:0005575 GO:0005220
is_a GO:0022838 GO:0005220
is_a GO:0022836 GO:0005220
part of GO:0051179 GO:0005220
is_a GO:0022834 GO:0005220
has_part GO:0005488 GO:0005220
has_part GO:0043178 GO:0005220
is_a GO:0015267 GO:0005220
part of GO:0070838 GO:0005220
part of GO:0008150 GO:0005220
part of GO:0034220 GO:0005220
part of GO:0035556 GO:0005220
part of GO:0044699 GO:0005220

4 Synonyms

Name Type
InsP3 receptor synonym
inositol-1,4,5-trisphosphate receptor activity synonym
GO:0008095 alt_id
IP3 receptor activity synonym