GO Term : GO:0005243 gap junction channel activity GO

Namespace:  molecular_function Obsolete:  false
description  A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

1 Ontology Annotations

GO Term Gene Name
GO:0005243 IPR002262

17 Parents

Identifier Name Description
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0055085 transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other
GO:0022857 transmembrane transporter activity Enables the transfer of a substance from one side of a membrane to the other.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GO:0015267 channel activity Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:1902578 single-organism localization A localization which involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0051234 establishment of localization The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
GO:0044765 single-organism transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving a single organism.
GO:0022803 passive transmembrane transporter activity Enables the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.
GO:0022829 wide pore channel activity Enables the transport of a solute across a membrane via a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts.
GO:0005243 gap junction channel activity A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes.

31 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0022829 GO:0005243
is_a GO:0022803 GO:0005243
is_a GO:0022857 GO:0005243
part of GO:0051234 GO:0005243
part of GO:0051179 GO:0005243
part of GO:0044763 GO:0005243
is_a GO:0015267 GO:0005243
part of GO:0008150 GO:0005243
is_a GO:0003674 GO:0005243
is_a GO:0005215 GO:0005243
part of GO:1902578 GO:0005243
part of GO:0009987 GO:0005243
part of GO:0044765 GO:0005243
part of GO:0044699 GO:0005243
part of GO:0006810 GO:0005243
part of GO:0055085 GO:0005243
part of GO:0005243 GO:0055077
is_a GO:0005243 GO:0086020
is_a GO:0005243 GO:0086020
is_a GO:0005243 GO:0086075
is_a GO:0005243 GO:0086075
is_a GO:0005243 GO:0086076
is_a GO:0005243 GO:0086076
is_a GO:0005243 GO:0086077
is_a GO:0005243 GO:0086077
is_a GO:0005243 GO:0086078
is_a GO:0005243 GO:0086078
is_a GO:0005243 GO:0086079
is_a GO:0005243 GO:0086079
is_a GO:0005243 GO:1903763

6 Synonyms

Name Type
connexin synonym
innexin synonym
innexin channel activity synonym
intercellular channel synonym
GO:0015285 alt_id
GO:0015286 alt_id