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GO:0003824
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catalytic activity
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Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
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GO:0008152
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metabolic process
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The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. |
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GO:0016829
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lyase activity
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Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. |
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GO:0009058
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biosynthetic process
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The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. |
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GO:0006796
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phosphate-containing compound metabolic process
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The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. |
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GO:0044237
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cellular metabolic process
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The chemical reactions and pathways by which individual cells transform chemical substances. |
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GO:0006807
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nitrogen compound metabolic process
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The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium. |
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GO:0006139
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nucleobase-containing compound metabolic process
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Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. |
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GO:0071704
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organic substance metabolic process
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The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. |
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GO:0006164
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purine nucleotide biosynthetic process
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The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. |
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GO:0009165
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nucleotide biosynthetic process
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The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates). |
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GO:0044238
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primary metabolic process
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The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. |
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GO:0009117
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nucleotide metabolic process
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The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates). |
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GO:0006725
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cellular aromatic compound metabolic process
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The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. |
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GO:0009152
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purine ribonucleotide biosynthetic process
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The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. |
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GO:0050790
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regulation of catalytic activity
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Any process that modulates the activity of an enzyme. |
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GO:0009190
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cyclic nucleotide biosynthetic process
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The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue. |
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GO:0016849
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phosphorus-oxygen lyase activity
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Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. |
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GO:0006163
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purine nucleotide metabolic process
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The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. |
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GO:1901137
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carbohydrate derivative biosynthetic process
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The chemical reactions and pathways resulting in the formation of carbohydrate derivative. |
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GO:0044249
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cellular biosynthetic process
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The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. |
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GO:0043086
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negative regulation of catalytic activity
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Any process that stops or reduces the activity of an enzyme. |
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GO:0045980
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negative regulation of nucleotide metabolic process
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Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. |
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GO:0009890
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negative regulation of biosynthetic process
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Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. |
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GO:0009987
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cellular process
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Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
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GO:0055086
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nucleobase-containing small molecule metabolic process
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The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. |
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GO:0006793
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phosphorus metabolic process
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The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4). |
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GO:0045936
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negative regulation of phosphate metabolic process
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Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates. |
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GO:0004016
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adenylate cyclase activity
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Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. |
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GO:0006171
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cAMP biosynthetic process
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The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). |
