21 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:0007165 | signal transduction | The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
| GO:0035556 | intracellular signal transduction | The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. |
| GO:0009966 | regulation of signal transduction | Any process that modulates the frequency, rate or extent of signal transduction. |
| GO:0051716 | cellular response to stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. |
| GO:0007154 | cell communication | Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. |
| GO:0009987 | cellular process | Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
| GO:0044763 | single-organism cellular process | Any process that is carried out at the cellular level, occurring within a single organism. |
| GO:0044699 | single-organism process | A biological process that involves only one organism. |
| GO:0008150 | biological_process | Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
| GO:0050896 | response to stimulus | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. |
| GO:0065007 | biological regulation | Any process that modulates a measurable attribute of any biological process, quality or function. |
| GO:0050794 | regulation of cellular process | Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
| GO:0050789 | regulation of biological process | Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. |
| GO:0023052 | signaling | The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered. |
| GO:0044700 | single organism signaling | A signaling process occurring within a single organism. |
| GO:0023051 | regulation of signaling | Any process that modulates the frequency, rate or extent of a signaling process. |
| GO:1902531 | regulation of intracellular signal transduction | Any process that modulates the frequency, rate or extent of intracellular signal transduction. |
| GO:0048583 | regulation of response to stimulus | Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. |
| GO:0010646 | regulation of cell communication | Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. |
| GO:0007249 | I-kappaB kinase/NF-kappaB signaling | The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. |
| GO:0043122 | regulation of I-kappaB kinase/NF-kappaB signaling | Any process that modulates I-kappaB kinase/NF-kappaB signaling. |
41 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| part of | GO:0043122 | GO:0007253 |
| is_a | GO:0043122 | GO:0007253 |
| is_a | GO:0043122 | GO:0008588 |
| negatively regulates | GO:0043122 | GO:0008588 |
| is_a | GO:0043122 | GO:0042345 |
| is_a | GO:0043122 | GO:0042346 |
| is_a | GO:0043122 | GO:0042347 |
| regulates | GO:0007249 | GO:0043122 |
| is_a | GO:0065007 | GO:0043122 |
| regulates | GO:0007249 | GO:0043122 |
| is_a | GO:1902531 | GO:0043122 |
| regulates | GO:0050789 | GO:0043122 |
| regulates | GO:0051716 | GO:0043122 |
| is_a | GO:0050794 | GO:0043122 |
| regulates | GO:0044763 | GO:0043122 |
| is_a | GO:0048583 | GO:0043122 |
| is_a | GO:0023051 | GO:0043122 |
| regulates | GO:0023052 | GO:0043122 |
| is_a | GO:0010646 | GO:0043122 |
| regulates | GO:0050794 | GO:0043122 |
| regulates | GO:0008150 | GO:0043122 |
| is_a | GO:0050789 | GO:0043122 |
| regulates | GO:0050896 | GO:0043122 |
| regulates | GO:0035556 | GO:0043122 |
| regulates | GO:0007165 | GO:0043122 |
| regulates | GO:0007154 | GO:0043122 |
| is_a | GO:0008150 | GO:0043122 |
| regulates | GO:0044700 | GO:0043122 |
| regulates | GO:0065007 | GO:0043122 |
| is_a | GO:0009966 | GO:0043122 |
