GO Term : GO:0014069 postsynaptic density GO

Namespace:  cellular_component Obsolete:  false
description  The postsynaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases. The postsynaptic density may be part of a neuron or a muscle cell or a glial cell.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

7 Parents

Identifier Name Description
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0045202 synapse The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
GO:0044456 synapse part Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
GO:0014069 postsynaptic density The postsynaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases. The postsynaptic density may be part of a neuron or a muscle cell or a glial cell.
GO:0098794 postsynapse The part of a synapse that is part of the post-synaptic cell.

13 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0044464 GO:0014069
part of GO:0098794 GO:0014069
is_a GO:0044456 GO:0014069
part of GO:0005575 GO:0014069
part of GO:0044456 GO:0014069
is_a GO:0005575 GO:0014069
part of GO:0044464 GO:0014069
part of GO:0045202 GO:0014069
part of GO:0005623 GO:0014069
has_part GO:0014069 GO:0044327
is_a GO:0014069 GO:0097481
is_a GO:0014069 GO:0097482
is_a GO:0014069 GO:0097483

2 Synonyms

Name Type
post-synaptic density synonym
post synaptic density synonym