GO Term : GO:0015350 methotrexate transporter activity GO

Namespace:  molecular_function Obsolete:  false
description  Enables the directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

2 Ontology Annotations

GO Term Gene Name
GO:0015350 IPR028339
GO:0015350 IPR030176

25 Parents

Identifier Name Description
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GO:0006811 ion transport The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006835 dicarboxylic acid transport The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006820 anion transport The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0071705 nitrogen compound transport The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015711 organic anion transport The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:1902578 single-organism localization A localization which involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0051234 establishment of localization The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
GO:0044765 single-organism transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0071702 organic substance transport The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.
GO:0015849 organic acid transport The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0046942 carboxylic acid transport The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
GO:0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GO:0042886 amide transport The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0090484 drug transporter activity Enables the directed movement of a drug into, out of or within a cell, or between cells. A drug is any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
GO:0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
GO:0015893 drug transport The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051958 methotrexate transport The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.
GO:0015350 methotrexate transporter activity Enables the directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.

24 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0051958 GO:0015350
is_a GO:0090484 GO:0015350
part of GO:0015711 GO:0015350
part of GO:0008150 GO:0015350
part of GO:0042886 GO:0015350
part of GO:0071705 GO:0015350
part of GO:0071702 GO:0015350
part of GO:0015893 GO:0015350
is_a GO:0005215 GO:0015350
is_a GO:0003674 GO:0015350
part of GO:0050896 GO:0015350
part of GO:0051234 GO:0015350
part of GO:0051179 GO:0015350
part of GO:0006835 GO:0015350
part of GO:0006810 GO:0015350
part of GO:0006811 GO:0015350
part of GO:0006820 GO:0015350
part of GO:0046942 GO:0015350
part of GO:0044765 GO:0015350
part of GO:0042221 GO:0015350
part of GO:0044699 GO:0015350
part of GO:1902578 GO:0015350
part of GO:0042493 GO:0015350
part of GO:0015849 GO:0015350

0 Synonyms