GO Term : GO:0030056 hemidesmosome GO

Namespace:  cellular_component Obsolete:  false
description  A cell-substrate junction (attachment structure) found in epithelial cells that links intermediate filaments to extracellular matrices via transmembrane complexes. In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

4 Parents

Identifier Name Description
GO:0030054 cell junction A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0030055 cell-substrate junction A cell junction that forms a connection between a cell and the extracellular matrix.
GO:0030056 hemidesmosome A cell-substrate junction (attachment structure) found in epithelial cells that links intermediate filaments to extracellular matrices via transmembrane complexes. In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces.

4 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0030055 GO:0030056
is_a GO:0005575 GO:0030056
is_a GO:0030054 GO:0030056
part of GO:0030056 GO:0061465

4 Synonyms

Name Type
epidermal attachment structure synonym
trans-epithelial attachment synonym
fibrous organelle synonym
hemi-adherens junction synonym