GO Term : GO:0033132 negative regulation of glucokinase activity GO
Namespace:  biological_process Obsolete:  false
description  Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

64 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0005975 carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
GO:0016310 phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
GO:0016772 transferase activity, transferring phosphorus-containing groups Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0006796 phosphate-containing compound metabolic process The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0016301 kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0016773 phosphotransferase activity, alcohol group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0006006 glucose metabolic process The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0004396 hexokinase activity Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate.
GO:0046835 carbohydrate phosphorylation The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0019318 hexose metabolic process The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0043086 negative regulation of catalytic activity Any process that stops or reduces the activity of an enzyme.
GO:0042325 regulation of phosphorylation Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.
GO:0005996 monosaccharide metabolic process The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
GO:0004340 glucokinase activity Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate.
GO:0051156 glucose 6-phosphate metabolic process The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0006109 regulation of carbohydrate metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.
GO:0044262 cellular carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
GO:0006793 phosphorus metabolic process The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
GO:0045936 negative regulation of phosphate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
GO:1901135 carbohydrate derivative metabolic process The chemical reactions and pathways involving carbohydrate derivative.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

90 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:1903300 GO:0033132
negatively regulates GO:0004340 GO:0033132
negatively regulates GO:0004340 GO:0033132
is_a GO:0065007 GO:0033132
is_a GO:0033131 GO:0033132
negatively regulates GO:0004396 GO:0033132
is_a GO:0009892 GO:0033132
regulates GO:0004340 GO:0033132
negatively regulates GO:0008152 GO:0033132
regulates GO:0005996 GO:0033132
regulates GO:0006006 GO:0033132
is_a GO:0050789 GO:0033132
regulates GO:0044238 GO:0033132
negatively regulates GO:0019200 GO:0033132
regulates GO:0044237 GO:0033132
regulates GO:0044710 GO:0033132
is_a GO:0006109 GO:0033132
is_a GO:0043086 GO:0033132
negatively regulates GO:0003824 GO:0033132
regulates GO:0008152 GO:0033132
is_a GO:0044092 GO:0033132
regulates GO:0008150 GO:0033132
negatively regulates GO:0016772 GO:0033132
negatively regulates GO:0016773 GO:0033132
is_a GO:0010563 GO:0033132
regulates GO:0019637 GO:0033132
regulates GO:0019318 GO:0033132
regulates GO:0071704 GO:0033132
is_a GO:0010675 GO:0033132
regulates GO:0004396 GO:0033132

5 Synonyms

Name Type
down regulation of glucokinase activity synonym
downregulation of glucokinase activity synonym
down-regulation of glucokinase activity synonym
inhibition of glucokinase activity synonym
glucokinase inhibitor synonym