GO Term : GO:0036261 7-methylguanosine cap hypermethylation GO

Namespace:  biological_process Obsolete:  false
description  Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

25 Parents

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0006396 RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0009451 RNA modification The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0043412 macromolecule modification The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
GO:0032259 methylation The process in which a methyl group is covalently attached to a molecule.
GO:0001510 RNA methylation Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0016070 RNA metabolic process The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0090304 nucleic acid metabolic process Any cellular metabolic process involving nucleic acids.
GO:0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:1901360 organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound.
GO:0046483 heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0010467 gene expression The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GO:0043414 macromolecule methylation The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.
GO:0036260 RNA capping The sequence of enzymatic reactions by which a cap structure is added to the 5' end of a nascent RNA polymerase II transcript. All RNA polymerase II transcripts receive a 7-methyl-G cap. Then for (at least) small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs), the7-methyl-G cap is hypermethylated to become a 2,2,7-trimethylguanosine (TMG) cap.
GO:0036261 7-methylguanosine cap hypermethylation Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.

29 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0036260 GO:0036261
is_a GO:0001510 GO:0036261
is_a GO:0032259 GO:0036261
is_a GO:0006807 GO:0036261
part of GO:0010467 GO:0036261
is_a GO:0006725 GO:0036261
is_a GO:0016070 GO:0036261
is_a GO:0071704 GO:0036261
is_a GO:0044237 GO:0036261
is_a GO:0008150 GO:0036261
is_a GO:0044238 GO:0036261
is_a GO:0008152 GO:0036261
is_a GO:0090304 GO:0036261
part of GO:0043170 GO:0036261
is_a GO:0006139 GO:0036261
part of GO:0071704 GO:0036261
part of GO:0008150 GO:0036261
part of GO:0008152 GO:0036261
is_a GO:0006396 GO:0036261
is_a GO:0009987 GO:0036261
is_a GO:0043414 GO:0036261
is_a GO:0043412 GO:0036261
is_a GO:0009451 GO:0036261
is_a GO:0034641 GO:0036261
is_a GO:0044260 GO:0036261
is_a GO:1901360 GO:0036261
is_a GO:0046483 GO:0036261
is_a GO:0043170 GO:0036261
part of GO:0036261 GO:0071164

8 Synonyms

Name Type
conversion of m(7)G to m(3)G synonym
2,2,7-trimethylguanosine cap formation synonym
hypermethylation of snRNA cap synonym
hypermethylation of snoRNA cap synonym
snoRNA capping synonym
m(7)G cap hypermethylation synonym
TMG cap formation synonym
snRNA capping synonym