GO Term : GO:0039589 suppression by virus of host TAP complex GO
Namespace:  biological_process Obsolete:  false
description  Any process in which a virus stops, prevents, or reduces the activity of the host TAP complex, a heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). The TAP complex functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum, where they are loaded onto the MHC class I. By inhibiting the TAP complex, the virus prevents viral particles being presented at the cell surface, and thus evades the host immune response.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

103 Parents

Identifier Name Description
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0006952 defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
GO:0009607 response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
GO:0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0006955 immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
GO:0071705 nitrogen compound transport The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0031347 regulation of defense response Any process that modulates the frequency, rate or extent of a defense response.
GO:0015833 peptide transport The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0019882 antigen processing and presentation The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
GO:0016032 viral process A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.
GO:0030683 evasion or tolerance by virus of host immune response Any process, either active or passive, by which a virus avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051607 defense response to virus Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
GO:0019048 modulation by virus of host morphology or physiology The process in which a virus effects a change in the structure or processes of its host organism.
GO:0002682 regulation of immune system process Any process that modulates the frequency, rate, or extent of an immune system process.
GO:0031348 negative regulation of defense response Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:1902578 single-organism localization A localization which involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0051234 establishment of localization The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
GO:0044765 single-organism transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0071702 organic substance transport The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0044764 multi-organism cellular process Any process that is carried out at the cellular level which involves another organism of the same or different species.
GO:0051704 multi-organism process A biological process which involves another organism of the same or different species.

143 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0039588 GO:0039589
is_a GO:0039504 GO:0039589
is_a GO:1901040 GO:0039589
regulates GO:0009605 GO:0039589
is_a GO:0009987 GO:0039589
regulates GO:0002252 GO:0039589
regulates GO:0002250 GO:0039589
regulates GO:0009607 GO:0039589
regulates GO:0044699 GO:0039589
regulates GO:0002376 GO:0039589
is_a GO:0016032 GO:0039589
negatively regulates GO:0042886 GO:0039589
negatively regulates GO:0046968 GO:0039589
is_a GO:0002832 GO:0039589
is_a GO:0002831 GO:0039589
regulates GO:0051707 GO:0039589
is_a GO:0075136 GO:0039589
is_a GO:0051049 GO:0039589
regulates GO:0019882 GO:0039589
regulates GO:0051704 GO:0039589
is_a GO:0052255 GO:0039589
negatively regulates GO:0051234 GO:0039589
regulates GO:0009615 GO:0039589
negatively regulates GO:0006810 GO:0039589
regulates GO:1902578 GO:0039589
is_a GO:0044068 GO:0039589
is_a GO:0090087 GO:0039589
regulates GO:0071705 GO:0039589
is_a GO:0051834 GO:0039589
negatively regulates GO:0043207 GO:0039589

1 Synonyms

Name Type
inhibition of host TAP by virus synonym