GO Term : GO:0039699 viral mRNA cap methylation GO

Namespace:  biological_process Obsolete:  false
description  Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a viral mRNA. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

111 Parents

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0006952 defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
GO:0009607 response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0009451 RNA modification The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
GO:0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006955 immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
GO:0043412 macromolecule modification The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
GO:0032259 methylation The process in which a methyl group is covalently attached to a molecule.
GO:0001510 RNA methylation Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0016070 RNA metabolic process The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
GO:0031347 regulation of defense response Any process that modulates the frequency, rate or extent of a defense response.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0016032 viral process A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.
GO:0080009 mRNA methylation The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule.
GO:0030683 evasion or tolerance by virus of host immune response Any process, either active or passive, by which a virus avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0045087 innate immune response Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051607 defense response to virus Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
GO:0019048 modulation by virus of host morphology or physiology The process in which a virus effects a change in the structure or processes of its host organism.
GO:0002682 regulation of immune system process Any process that modulates the frequency, rate, or extent of an immune system process.
GO:0031348 negative regulation of defense response Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0090304 nucleic acid metabolic process Any cellular metabolic process involving nucleic acids.

138 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0036451 GO:0039699
is_a GO:0044033 GO:0039699
is_a GO:0039503 GO:0039699
negatively regulates GO:0006950 GO:0039699
is_a GO:0052261 GO:0039699
negatively regulates GO:0006952 GO:0039699
is_a GO:0032259 GO:0039699
regulates GO:0009615 GO:0039699
negatively regulates GO:0006955 GO:0039699
negatively regulates GO:0045087 GO:0039699
is_a GO:0001510 GO:0039699
is_a GO:0002683 GO:0039699
is_a GO:0002682 GO:0039699
is_a GO:0044003 GO:0039699
is_a GO:0044764 GO:0039699
is_a GO:0044403 GO:0039699
is_a GO:0052306 GO:0039699
is_a GO:0052309 GO:0039699
is_a GO:0090304 GO:0039699
is_a GO:0006807 GO:0039699
is_a GO:0009987 GO:0039699
part of GO:0044403 GO:0039699
regulates GO:0009987 GO:0039699
is_a GO:0016032 GO:0039699
is_a GO:0044237 GO:0039699
is_a GO:0044238 GO:0039699
regulates GO:0051607 GO:0039699
is_a GO:0002832 GO:0039699
is_a GO:0002831 GO:0039699
is_a GO:0016556 GO:0039699

1 Synonyms

Name Type
IFIT mRNA restriction evasion by virus synonym