GO Term : GO:0043004 cytoplasmic sequestering of CFTR protein GO
Namespace:  biological_process Obsolete:  false
description  The selective interaction of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein with specific molecules in the cytoplasm, thereby inhibiting its transport to the cell membrane.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

88 Parents

Identifier Name Description
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0005737 cytoplasm All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0016192 vesicle-mediated transport A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
GO:0006886 intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
GO:0048193 Golgi vesicle transport The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
GO:0015031 protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006893 Golgi to plasma membrane transport The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.
GO:0046907 intracellular transport The directed movement of substances within a cell.
GO:0061024 membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008104 protein localization Any process in which a protein is transported to, or maintained in, a specific location.
GO:0072659 protein localization to plasma membrane A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0051641 cellular localization A localization process that takes place at the cellular level; as a result of a cellular localization process, a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:1902578 single-organism localization A localization which involves only one organism.
GO:1902580 single-organism cellular localization A cellular localization which involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0051234 establishment of localization The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
GO:0044765 single-organism transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving a single organism.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0071702 organic substance transport The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.

140 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0051220 GO:0043004
is_a GO:0043002 GO:0043004
regulates GO:0090150 GO:0043004
is_a GO:0051128 GO:0043004
regulates GO:0045184 GO:0043004
is_a GO:0051129 GO:0043004
negatively regulates GO:0072657 GO:0043004
negatively regulates GO:0072659 GO:0043004
negatively regulates GO:0090002 GO:0043004
is_a GO:0050794 GO:0043004
is_a GO:0070201 GO:0043004
negatively regulates GO:0071840 GO:0043004
is_a GO:1903076 GO:0043004
is_a GO:1903077 GO:0043004
regulates GO:0008150 GO:0043004
is_a GO:0048519 GO:0043004
negatively regulates GO:1902578 GO:0043004
regulates GO:0006810 GO:0043004
regulates GO:0006892 GO:0043004
regulates GO:0006893 GO:0043004
is_a GO:0051235 GO:0043004
negatively regulates GO:0016043 GO:0043004
is_a GO:0050789 GO:0043004
regulates GO:0051234 GO:0043004
regulates GO:0061024 GO:0043004
is_a GO:0090317 GO:0043004
part of GO:0051641 GO:0043004
negatively regulates GO:0043001 GO:0043004
negatively regulates GO:0043000 GO:0043004
negatively regulates GO:0044699 GO:0043004

9 Synonyms

Name Type
sequestration of CFTR (cystic fibrosis transmembrane conductance regulator protein) in cytoplasm synonym
storage of CFTR (cystic fibrosis transmembrane conductance regulator) protein in cytoplasm synonym
cytoplasmic retention of CFTR (cystic fibrosis transmembrane conductance regulator) protein synonym
cytoplasmic sequestering of cystic fibrosis transmembrane conductance regulator protein synonym
cytoplasmic sequestration of CFTR (cystic fibrosis transmembrane conductance regulator protein) synonym
cytoplasmic storage of CFTR (cystic fibrosis transmembrane conductance regulator) protein synonym
maintenance of CFTR protein location in cytoplasm synonym
retention of CFTR (cystic fibrosis transmembrane conductance regulator) protein in cytoplasm synonym
sequestering of CFTR (cystic fibrosis transmembrane conductance regulator protein) in cytoplasm synonym